Bioclinic Naturals 5-MTHF & B12 Biologically Active Folic Acid - 60 Lozenges

Bioclinic Naturals 5-MTHF & B12 provides the most biologically active forms of two complementary B vitamins. (6S)-5-Methyltetrahydrofolate Acid or MTHF is the active form of folate at the cellular level, the form found in circulation and the only to cross the blood brain barrier. It does not need to be converted to an active form by the enzyme methylene tetrahydrofolate reductase or MTHFR, known to have common single-nucleotide polymorphisms that impair enzymatic activity by as much as 70 percent. Furthermore, quatrefolic acid administration has been associated with higher peak 5-MTHF levels than both folic acid and calcium 5-MTHF, with higher plasma folate levels even in those with high functioning MTHFR polymorphisms. While (6S)-5-Methyltetrahydrofolate Acid does not mask a B12 deficiency as folic acid supplementation alone may, these two vitamins have complementary roles in methylation pathways that warrant combined use. Methylcobalamin is the principle circulating form of B12, and is a direct cofactor for B12-dependent enzymes. It has direct biological activity, in contrast to cyanocobalamin, which is synthetically derived. When combined with other B vitamins, B12 has been shown to be more effective.

• Bioclinic Naturals 5-MTHF & B12 contains biologically active folic acid in the form 5-Methyltetrahydrofolic Acid
• Each lozenge also provides 50 mcg methylcobalamin, the primary circulating and biologically active form of vitamin B12
• In a base of active plant extracts, including many organic vegetables, and other bioactive plant compounds, including Theracurmin curcumin
• Lozenges are suitable for vegetarians, and allow for easy dosing